A Natural, Inexpensive, Easily Accessible, Safer Treatment for Depression?

February 12, 2013
Print This Post Print This Post

iStock_000017469454XSmallNot if pharmacists have their way! Action Alert!

Pharmacists Planning Service (PPS), a “public health, consumer, and pharmacy education” nonprofit, is petitioning the FDA to change the designation of St. John’s Wort from “herbal dietary supplement status” to “behind pharmacy counter status” (BPCS)—a designation that requires pharmacist consultation—citing dangerous side effects and drug interactions.

PPS’s claim is specious. St. John’s Wort (Hypericum perforatum) is far safer than prescription depression medications. Unlike those medications, it has not been linked to addiction, suicide, or violent behavior. It also appears to be effective and has been used for many years in Germany and other countries to treat mild depression, especially in children and adolescents. A meta-analysis found that “the hypericum extracts tested in the included trials a) are superior to placebo in patients with major depression; b) are similarly effective as standard antidepressants; c) and have fewer side effects than standard antidepressants.”

The “fewer side effects” issue is an important one. A 2000 study found that SJW “was superior to fluoxetine [Prozac] in overall incidence of side-effects, number of patients with side effects, and the type of side effect reported.” Similar studies found SJW superior to other SSRIs (selective serotonin reuptake inhibitors) as well. This actually understates the side effects risk issue for adolescents and young people. Black box warnings on SSRI’s warn of suicide risk for these groups; they should warn of violent behavior risk but do not. The FDA does not want to admit the evidence linking the drugs to violent behavior, including mass shootings.

Another, older class of antidepressants is TCAs (tricyclic antidepressants), which, according to a study from early 2011, are at least as effective against depression as SSRIs (this is faint praise, since SSRI’s have not been proven to be very effective). Although TCAs are slowly being replaced by SSRIs, they are still extremely popular: according to Pharmacy Times, in 2011 the most commonly prescribed drug in the US was a TCA called amitriptyline (sold under the trade names Tryptomer, Elavil, Tryptizol, Laroxyl, Saroten, Sarotex, Lentizol, and Endep).

Amitriptyline’s side effects range from anxiety, panic attacks, chest pain, sudden numbness to one side of the body, sudden severe headache, and problems with vision, speech, or balance, to suicidal ideation, hallucinations, seizures, and bleeding from the nose, mouth, vagina, or rectum.

Antidepressant drugs of all kinds are huge money-makers for drug companies: Antidepressants are used by 11% of Americans. Use has increased 400% over ten years. And, of those taking them, 60% report using for more than two years. Seven of the top eighteen prescribed drugs are antidepressants.

Because it is safe, effective, and relatively inexpensive, SJW poses serious competition to the US pharmaceutical industry. The thought of more and more people turning to an over-the-counter herb instead of relying on pharmaceutical drugs has pharmacists running scared. In addition, there is currently an oversupply of pharmacists, which has had the effect of reducing pharmacists’ wages by 20% on a national scale. This oversupply will only continue as e-prescribing increases, the pharmacy technician’s role is expanded, and pharmacy benefit managers restrict distribution channels and force patients into the mail-order system. This would seem to be a case where PPS does not really have consumers’ interests in mind, but instead are trying to protect their own bottom line from competition.

We do not know the exact percentage of prescriptions that are filled by pharmacists (as opposed to pharmacy technicians), though certainly the majority are. We do, however, know that prescription antidepressants were the second most frequently dispensed prescriptions in the US in 2010 (they were beaten out by statin drugs and other lipid regulators), with over 253.6 million antidepressant prescriptions filled. SJW is direct competition because it doesn’t require prescription, and therefore doesn’t require a visit to the pharmacy for access.

The math is simple: higher SJW sales means fewer antidepressant prescriptions, which means fewer prescriptions for pharmacists to fill, which means fewer pharmacists employed.

If PPS is successful in its petition, St. John’s Wort will no longer be an easily accessible alternative to prescription drugs. PPS has a history of putting pharmacists between consumers and even over-the-counter products as much as possible—for example, the organization advocates mandatory pharmacist/consumer consultations and patient history checks.

Let’s look further at PPS’s claim that SJW is unsafe. According to NIH’s National Center for Complementary and Alternative Medicine (NCCAM), SJW’s potential side effects are mild; they include dry mouth, dizziness, gastrointestinal symptoms, and an increased sensitivity to sunlight. PPS claims that SJW caused one death through an interaction with cyclosporine. However, the author of the article PPS quoted as evidence was unable to provide us with an accurate citation after we reached out to him. FDA does not have this death on file.

The petition mentions that two recently approved hepatitis C drugs contain a SJW drug interaction warning in their package inserts, and notes that SJW should be avoided if the patient is taking certain other drugs. But since 2000 the American Herbal Products Association (AHPA) has had in place a guidance policy recommending that SJW products be labeled with a warning not to take SJW while taking any prescription drugs without the advice of the prescribing physician. In other words, PPS is simply acknowledging what the supplement industry has known for many years: some St. John’s Wort ingredients can interact with certain drugs—information that is already disclosed through the broad use of the warning label.

SJW should not be placed behind the counter. Not only is it a safer alternative to prescription antidepressants—and there are very few treatments for mild depression on the market at all—but making its purchase contingent on a consultation with a pharmacist also places one more hurdle between consumer and natural treatments. Such a move might dissuade the consumer from taking SJW (which is, of course, PPS’s hope). It would also give a false impression of that SJW is dangerous.

The very idea that pharmacists are in a position to counsel on the use of SJW is ridiculous. Quite apart from the conflict of interest, pharmacists in the US, unlike in Germany, know nothing about herbs. They are in no way qualified to give advice on the subject.

We wish that pharmacists were qualified to give advice on herbs and other supplements. We also wish that so-called drug stores were healthy places that did not make almost all their money  from a combination of  junk food and drugs. In this respect, these stores are emblematic of what is wrong with American health: first create a problem with poor diet and then mask the problem with prescription drugs that control symptoms,  do not cure, and may be highly toxic themselves. This is one money-making machine we do not need.

There is no specific timeline for this petition: FDA has not yet responded to PPS’s petition, and it is still open for public comment. Action Alert! Please tell FDA that St. John’s Wort is a safe and time-tested remedy for mild depression, that the safeguards already built into the system with the warning on the label are completely adequate, and that druggists do not have the qualifications to play any such advisory role. No reclassification to “behind the counter status” is even remotely warranted. Please write to the FDA today!

Take Action

2/13/2013: An earlier version of this article stated that TCAs are a newer class of antidepressants than SSRIs. TCAs are actually older, which the article has been edited to reflect.

56 Responses to “A Natural, Inexpensive, Easily Accessible, Safer Treatment for Depression?”

  1. Steve Laux says:

    St. John’s Wort needs to be left available as an alternative to those for whom normally prescribed drugs have adverse effects. There are many positive components to the use of St. John’s Wort, the best of which, under similar circumstances to any drug (in other words we compare grapefruits to grapefruits), is the more natural, safer action of the herb. Requiring dispensing by a pharmacist is wholly inappropriate and would unnecessarily add to the cost of the herbal preparation and to the inconvenience of acquiring some. We really need to reach a point where we start regaining confidence in a government we are beginning to perceive as overreaching and know that they can leave some rights still with the customer. Nothing has changed over the years with St. John’s Wort and it’s means of action/characteristics…what has changed is the strategy of the Pharma industry to attempt to wrest total control from consumers in order to reap the profits.

       0 likes

  2. Katie says:

    You may want to mention that SJW makes the birth control pill less effective before encouraging people to take it. It’s important to share the negatives of natural remedies, too.

       2 likes

  3. Les Peterson, D.C. says:

    As the author states, this is really the heart of the matter, :”We also wish that so-called drug stores were healthy places that did not make almost all their money from a combination of junk food and drugs…these stores are emblematic of what is wrong with American health: first create a problem with poor diet and then mask the problem with prescription drugs that control symptoms, do not cure, and may be highly toxic themselves.”
    It would appear the near toxic environment, contaminated food, Madison Avenue’s relentless hammering of susceptible individuals to eat poorly, and Big Pharma’s eagerness to be ready, willing and able to attempt to supress the symptoms at high margins, is in essense the greatest wealth transfer currently in play. It is a swindle of global proportions that funnels a family’s assets not to heirs, or to charities, but to doctors, hospitals, insurance companies, pharmacy, nursing homes, and finally and prematurely, the mortuary.
    The evidence available seems to suggest recent healthcare legislation only further institutionalizes the biggest offenders.

       5 likes

  4. Ivonne says:

    I used st john’s wort for my major/severe depression and was able to ween off completely after three years. I’m not sure if this is too long to take St john’s wort but there are people who end up takas there have been some studies done about the use of st john’s wort and cataracts later in life. In fact, reading about these studies motivated me to stop using it. I must say, that it did help help me a lot

       1 likes

    • Ivonne says:

      I was not able to finish writing my comment!! Anyways, I took St. john’s wort for three years for severe/major depression with no problem and was able to stop after three years with very little withdrawal issues. Any time I tried to stop before that, I could not. I also used in combination with other natural therapies such as juicing, yoga, DBT, and naturally sourced vitamins. My concern is that I have heard of a study that linked St. john’s wort to cataracts in people who used it for over a year. Anybody heard about that? I’m not sure if that’s just another scare tactic by the drug pushers but it’s something to look into. I don’t feel that my vision is damaged at this point but cataracts usually take some time to develop. Some forms of SJW are very potent and you do have to be careful especially with other medications and supplements. I knew that it was time to stop when I felt the problems I was using it to treat were actually being caused by it. I started to experience panic and severe anxiety out of the blue that I think was being triggered by the SJW. Sure enough, once I stopped taking it, I felt much better. I don’t know if SJW “cured” me or if it was some of the other remedies or a combination I but I am definitely a different person now.

         0 likes

  5. There are lots of herbs that are helpful for depression– a number of the adaptogenic herbs are quite helpful. I found relief for my moderate depression by changing to the blood type diet (I was vegetarian, which exacerbated my depression– when I stopped eating wheat and dairy and started eating red meat again it reversed my depression, fatigue, arthritis and respiratory problems), and eventually adding the adaptogens best for my blood type(O). St. John’s wort is actually not so good for my blood type, though it is excellent for some other blood types. I prefer eleuthero, schisandra and/or rhodiola. They also have other benefits, such as bolstering my immune system.

       3 likes

  6. Tricyclic antidepressents are OLDER than SSRI’s. They’ve been around forever, they are poor antidepressents (although they may make you sleep better since they make you tired and fat). and you have to wean off them. Believe me, I’ve tried taken several types. They are as useless and dangerous as SSRI’s.

    Bad advice.

       2 likes

    • ANH-USA says:

      Hi Donna–You’re right, TCAs are older than SSRIs. The article has been edited to reflect this. Thanks, ANH

         2 likes

      • Marilyn says:

        St. John’s Wort did not work for me. Try SAMe a supplement that you buy anywhere. Discovered in Italy in the 50’s. Took US decades to discover it. Another supplement is Rhodiola that now comes in liquid. Both are for depression (not Rx). Hope this helps!

           1 likes

  7. Beverly Stone says:

    Don’t make natural cures harder and harder to get for the general public. Quit supporting big pharmaceutical drugs which are hundreds of times more expensive and which have many SERIOUS side effects.

    Use common sense. St. John’s Wort has been used successfully in EUrope for years!

       0 likes

  8. Dr Gayle says:

    Where did you get the idea that TCA’s are a newer class of antidepressants? These have been around for decades.

       0 likes

  9. Marie Louise Smith says:

    Please do not put St. Joh’s Wart behind the counter/prescription only. The pharmaceutical control of safe herbs is unnecessary, and unethical. Several proposed policies in the U.S. regarding pharmaceutical companies (and food companies – Monsanto, for example) are threatening freedom of choice and public welfare. This choice would benefit only a few people -the pharmacists financially, while potentially harming the majority.

       1 likes

  10. Vivian Johnston says:

    St. John’s Wort (Hypericum perforatum) is far safer than prescription depression medications. Unlike those medications, it has not been linked to addiction, suicide, or violent behavior. It also appears to be effective and has been used for many years in Germany and other countries to treat mild depression, especially in children and adolescents.
    Please leave St.Johns’s Wort as a herbal dietary supplement.

       1 likes

  11. Tommy says:

    I fell 40 feet and broke 15 bones, including 3 vertabrae in my back. After 5 surgeries, I made a almost full recovery and returned to work. Many years later I started experiencing severe pain in my lower back and it was determined that I now had 4 herniated discs. My doctor prescribed Elavil for me because he said it sometimes works on chronic pain. He told me to take a half a pill (pills are 50mg. each) at bedtime to start with. Eventually working my way up to 2 pills, twice a day. I was unable to get past the initial dosage of 25 mg. as I could not wake up in the morning. I was drowsy for a good half a day, the day after taking one. Similar to the Nyquil hangover you get when taking that product. I quit taking them and told the doctor there is no way I would ever be able to take 200 mg. a day of this stuff without passing out while driving. One week was long enough for me to know that these pills are not good for you.

       1 likes

  12. Gertrude says:

    I believe you lack certain knowledge about SJW. Although great for mild depression, doing nothing for deep depression, adverse effects have been known for quite a while now. When taking SJW it effect other medication you are taking, which can lead to dangerous situations. Herbs are not always innocent, one has to know what to take and in what condition not to take certain herbs. As SJW grows everywhere, banning it to an overthecounter subscription, might prove difficult.

       1 likes

  13. Please, leave St John’s Wort (JSW) as it is: a botanical supplement, not a drug. Consumers can decide for themeselves to use or not use this non-toxic substance.

       1 likes

  14. I’m with you on this, but what in the world makes you think that tricyclics are a “newer” class of antidepressants? Tricyclics were around long before SSRIs, dating back to the 1950s in fact, and were the second group of antidepressants to be developed after the MAOIs.

       0 likes

  15. Pamela Willliams says:

    The FDA needs to remember that it has a duty to protect citizens, not profit making corporations! Consumers need natural remedies, not dangerous drugs!

       1 likes

  16. dlowen says:

    You do at least admit you do not know. Regarding how many prescriptions are filled by pharmacists as opposed to technicians, the answer, apart from the military or other special cases not regulated by state boards of pharmacy, is pharmacist 100%, technician 0%. Technicians may perform many technical duties, but they cannot dispense any prescription medications, period.

    TCA’s are a newer class of antidepressant? Really? They were discovered in the 1950’s. They have largely been abandoned in favor of newer drugs that are more tolerated. Amitriptylline is still broadly used for other conditions and has a very favorable side effect profile in low doses. These doses are sub-therapeutic for depression, but are very helpful in a variety of other conditions.

    SSRI’s have not been proven to be very effective? Where are the scientific studies regarding St. John’s Wort? The evidence for SSRI’s efficacy is monumental compared to St. John’s Wort. Please evaluate with the same measure. (By the way, the ONLY acceptable way to scientifically evaluate the efficacy of two agents is in head-to-head studies.)

    The major problem with St. John’s Wort is not side effects, but drug interactions. This preparation induces the cytochrome p450 enzyme system, including both the cyp3a4 and cyp2c19 enzymes which are both important in the metabolism of a variety of medications. It can create toxicities and reduced efficacy in a variety of prescription medications.

    Pharmacists are not qualified to give advice on herbs, but the pimple faced high school student working in the health food store is? Your whole argument is ludicrous. Pharmacists are trained to evaluate drug studies. The whole problem is that herbs are not thought of as drugs even when they are being used to treat such complicated medical conditions as depression. If St. John’s Wort is superior to SSRI’s or other FDA approved antidepressants, let’s see some rigorous, head-to-head scientific trials…

       1 likes

    • Dr. B says:

      Spoken by a true drug pusher!! Listen to what you are saying. You are worried about drug interactions!! Why not get the people healthier, and focus on moving them away from the deadly game of Pharma roulette? People have the ability, in most cases, to become healthier and get off drugs if a qualified person helps them. I know first hand how hard it is to get out of that world, but it is so rewarding when you do! After a bone marrow transplant and several rounds of Chemo, I was told that I would have to take 8 different drugs for the rest of my life, or “you will die”!! At first, I complied and took the drugs. I watched my health decline for the next year, and nearly died. At that point I decided I had no quality of life on the drugs, so I decided to stop taking the drugs, and risk dying! The Doctors would not help me get off them, so I just stopped taking them. I do NOT recommend that anyone do that! The withdrawal symptoms were a living hell, but I now enjoy a drug free and healthy life! I take my supplements, eat well, and exercise regularly. I have since made it my mission to “rescue” people from the greedy grip of Big Pharma and the drones (Doctors) that push their dangerous drugs. I can tell you from experience that people are happier, healthier, and making better choices about lifestyle when they are not drugged into stupidity!!
      Whether or not this power grab by the Pharmacists happens or not, I will still use herbs, supplements, and proper nutrition to get people healthier and happier than your people could ever dream of!! Just remember, true health and healing come from the inside out, never from the outside in!

         4 likes

    • zack says:

      So with the drug interactions will I have to buy grapefruit from a pharmacist too? Good job disparaging sales people at health food stores, adds a lot of wieght to your argument. A simple warning would suffice on the label. Your argument would mean any food stuff that could interact with a drug must be dosed out by a pharmacist is troubling. Drugs have the first right of passage eh?

         1 likes

    • Andreia says:

      I don’t know where you live, but in North Carolina, most of our prescriptions are filled by Pharmacy Techs. After they are filled, they are double-checked with the Pharmacist. My sister, who is a Pharmacist, verified that approx. 90% of prescriptions are filled by Pharmacy Techs.

      Secondly, just because something is “natural” doesn’t mean that it’s good for you. SJW only helps very mild depression; not the moderate or severe depression that a lot of people have. Also, a lot of patients try adding SJW with their pharmaceutical prescriptions. Not only does SJW have some potentially bad side effects, it can also trigger hypomanic and manic behavior in those who are predisposed to it.

      I think it should be monitored.

         2 likes

    • Julie R.Ph says:

      You misspelled amitriptyline.

      It is possible to state your point without sounding snarky. I hope you don’t condescend to your patients in the same manner.

      As a pharmacist, I don’t believe SJW should be placed behind the counter. Pharmacists are available to consult if there is a question about efficacy, drug interactions, etc. We have access to a wealth of information regarding natural medicines and supplements with sites like the Natural Medicines Comprehensive Database.

      More government regulation and restriction does not equal a safer public. Example: pseudoephedrine has been behind pharmacy counters for years and yet meth labs proliferate.

         0 likes

  17. Michael Harris says:

    Please allow natural plants (herbs) and plant products to remain free from restriction. There should always be a clear boundary between pharmaceutical and herbal communities to provide people with a distinct choice.

       0 likes

  18. EM says:

    With all due respect, TCAs came long before SSRIs. Elavil has been around for what seems like forever. Though many of the newer members of this class of drugs are relatively recent, the class itself is not.

       0 likes

  19. MaryAnn Waits says:

    Please keep this herbs accessibility as it presently is. No need to change.

       0 likes

  20. Nancy Claire says:

    St. John’s Wart has been used for mild depression for many years and there are no recorded suicides, or aggressive behavior. You need to keep SJW available as an over-the-counter affordable remedy for the American public.
    Thank you for listening.

       0 likes

  21. Cuyler Brooks says:

    My doctor gave me amitriptyline for idiopathic peripheral neuropathy (”we don’t know why your feet burn”), saying that it had the least side effects of the antidepressants – one tiny tablet was too many for me. I suppose I could try St.John’s Wort – but I don’t believe the problem is psychosomatic.

       0 likes

    • Les Peterson, D.C. says:

      It might be useful to look into Alpha Lipoic Acid, preferably in the form of R-Lipoic Acid, and Acetyl L Carnitine to control symptoms of your neuropathy. Studies on diabetics have been promising, but I am not sure it will extrapolate to IPN.

      Bets regards.

         0 likes

  22. Debbie Baran says:

    There is an error here. Tricyclic anti-depressants are not a newer class of anti-depressants. SSRI’s are newer than the tricyclics and have fewer side effects than tricyclics. SSRI’s are prescribed more often than tricyclic anti-depressants. Please get your information accurate when publishing something of such great importance. I am a proponent of alternative treatments and educate my clients in holistic health. Yes, there are benefits of using SJW in treating some depression, but not all.

       0 likes

  23. Haddington O'Heart says:

    We’re tired of this horse (excrement)! If the FDA/Big Pharma shills think they can get away with this one, they are dead wrong. Just because They are on Prozac, doesn’t mean that the whole of America is. So, if they think they can pull St. John’s Wort from the shelves of healthfood stores and stick it behind pharmacists’ counters, just because they are losing business…

       0 likes

  24. Louise Carson says:

    Please use caution in wriing about the dangers of antidepressants. They have saved lives more than they have endangered them. Even Saint Johns Wort has its problems and should be used wisely. I would always use the more natural option if possible but it’s not always the most effective.

    But there is no need to take restricive action against this natural remedy that may work well for many people.

       0 likes

  25. Jeremy says:

    Okay I have not yet read the article, but I happened upon a phrase calling tricyclics “a newer generation of antidepressants”

    Tricyclics are the OLDEST type of antidepressants.

    It doesnt give me hope that the rest of this article will be accurate.

       0 likes

  26. Brenda Adams says:

    Your actions show you care more about money than you do about human beings! Americans won’t let you get away with taking away yet one more right over control of what we put into our bodies. If we have to grow our own St.Johns Wort in our back yards illegally, so be it! Then this country will have revolution like you’ve never seen. We’re on the edge already. Push if you dare!

       0 likes

  27. William says:

    SJW studies on PubMed:

    http://www.ncbi.nlm.nih.gov/pubmed/22593920

       0 likes

  28. Adina says:

    This is absurd! Pharmacists don’t have knowledge of herbs and should not be counseling anyone about them. Leave that to the herbalists.

       1 likes

  29. Mark Brockway says:

    As a pharmacist who actually knows a lot about herbs and supplements (far more than your authors), I take offense to this article. I do not support that St. John’s Wort should be behind the counter, but this article makes such sweeping generalizations of ignorance concerning the pharmacy profession that I am disgusted. Many of us don’t work in drugstores. Try writing a more intelligent article next time and don’t attack pharmacists. We are actually on your side more than you think and we have no agenda in terms of trying to fill as many prescriptions as possible. Most of us are very anti drug, because we know all about them. I’m really sick and tired of our profession being stereotyped as “evil druggists” working in drugstores and pushing pills. I happen to work in an ICU and I help save lives on a daily basis. So please, be more courteous and professional in the future.
    Mark Brockway, PharmD, RPh

       4 likes

  30. Rodema Ashby says:

    Thx 4 the info.

       0 likes

  31. Patty Boyer says:

    I suffer from depression that is much more severe. While I would love to find a natural treatment for it, neither St. Johns Wort nor SAME works for me. Please look for something that works for people like me. (Although the last diagnosis I saw was anxious depression, I think I am actually manic-depressive. I’ve just never to my knowledge been treated for the mania.)
    This is a “please help if you can” email…

       2 likes

  32. cbc says:

    Although I think that I read that St.John’s Wort can create problems with Heart Medicines (other than those few mentioned here ), I DO BELIEVE that we ALL should be allowed to make these choices ourselves….without need for “prescriptions” and WITH “recommendations” from Doctors and Pharmacists. It’s MY LIFE after all. AND…I don’t accept ALL the Doctor’s “Prescriptions” either !
    (dang-near Killed me a couple of times….when I was hospitalized with my Heart-Troubles and unknowlingly received medicines that I KNEW weren’t good for me ! )

    I’m very tired of our “dictatorial” Medical Processes !
    They won’t fix my inguinal hernia…because of my Heart. BUT, IF I survivedd the operation…I could get MORE EXERCISE and strengthen my Heart ! As it is NOW….I’m doomed to pain and withering-away !

    MY Body…MY Life…MY Choices !!!

       0 likes

  33. cheryelle crane says:

    I think the FDA needs to look back over all the prescription medications for depression and reassess how healthy they are for people. Depression should be treated not managed.

       1 likes

  34. Allen Larson says:

    Please do not change the designation of St. Johns wort to “behind the counter status”.

       0 likes

  35. Levanah says:

    This article states that tricyclics are a “newer class of antidepressants” than SSRIs, when in fact tricyclics are an older class of antidepressants that was in use for many years before SSRIs were introduced…and which target different biological activities.

    I must tell you that, as someone most interested in the possibility of using herbs and other nutrients in place of pharmaceuticals, it makes me feel skeptical about the reliability of other information in an article like this when I see such a glaring error. I very much want to see you flourish as a source of good solid information, not rhetoric calculated to inflame without any reliable foundation in accuracy. I will be following you further for a while to see whether this is what you can become.

       1 likes

  36. sue harrison says:

    Should be left as it is !!!

       0 likes

  37. Art Smith says:

    If I’m recallling correctly,I believe I read that St Jhns Wort can inhibit the metabolism of serotonin.There should be plenty of alternative remedies…………………………..Art

       0 likes

  38. Shasha says:

    Hi, I need to raise oxygen in my brain to help depression/anxiety/panic/suicidal thoughts. I do that by eating no gluten/dairy/soy/sugar and taking vitamins/good oils and LDN which helps to absorb more nutrients and rebuilds my cells. EDTA/DMPS IV chelations help remove heavy metals that block thyroid and more chemical reactions in my body. I need Armour thyroid, Lithium orotate, 2000mg of fish oil, 5000IU of Vit D3, Vit B12 methylcobalamin shot and more to be ok. Rhodiola, B vitamins, Coenzyme Q10, Krill oil, lecithin, creatine monohydrate and more help me.

       0 likes

  39. Heather says:

    We HAVE to turn the language around. St John’s Wort is an herb, and one that is not dangerous. On the other hand, prescription pharmaceuticals are dangerous until thoroughly proven otherwise. Thus, it is not that, “SJW caused one death through an interaction with cyclosporine”. Rather, cyclosporine caused one death through interaction with SJW. Also, it is the responsibility of the prescription med to carry the warning. It is the unsafe chemical that is so dangerous as to require a prescription, after all. People need to hear things the correct way.

       2 likes

  40. Nancy Newman says:

    Are you sure that TCA’s are a “newer” form of antidepressants? Unless I misread that, you may want to check it.

       1 likes

    • ANH-USA says:

      Hi Nancy–Thanks for pointing this out to us! You’re correct: TCAs are not a “newer” form of antidepressants; the article has been edited to reflect this. Best, ANH

         1 likes

  41. Bruce says:

    St. John’s Wort for depression is digested male bovine excretia.

       0 likes

  42. John says:

    This articles says that TCAs are a new class of drugs. That’s false

       1 likes

    • ANH-USA says:

      Hi John–Thanks for pointing this out to us. The article has been edited to reflect the fact that TCAs are not a new class of drugs. Best, ANH

         1 likes

  43. Ann Fuller says:

    Speaking of accurate citation…The research that I have read states that SJW is effective as SSRI for mild to moderate depression NOT major depressive disorder (MDD) and I see no reference. I want to support an effort that is based on facts and right now this is in accurate as far as my research reveals.

       1 likes

    • ANH-USA says:

      Hi Ann: Thanks for your comment! Here’s the citation on ‘A meta-analysis found that “the hypericum extracts tested in the included trials a) are superior to placebo in patients with major depression; b) are similarly effective as standard antidepressants; c) and have fewer side effects than standard antidepressants:”’ http://www.ncbi.nlm.nih.gov/pubmed/18843608 (This study is also hyperlinked in the article text).

         1 likes

  44. Jan Steinman says:

    I have found Rhodiola rosea to be very helpful. It helps you adapt to stress, and aids alertness.

       0 likes

Leave a Reply

Comment Policy:
ANH-USA provides a comment forum for our readers to share their constructive thoughts and criticisms about our newsletter articles and engage in civil debate with other readers. All comments are pre-moderated regardless of author. We never censor comments based on political or ideological point of view. We only remove those comments that are abusive, off-topic, use foul language, include personal attacks, or are otherwise discourteous and uncivil. Please do not post comments in ALL CAPS; on the internet this is considered "shouting."

 characters available

Follow us on...